• Delivering analytical and characterisation excellence in nanomaterial risk assessment: a tiered approach

    Delivering analytical and characterisation excellence in nanomaterial risk assessment: a tiered approach

  • Introducing confidence, adaptability and clarity into nanomaterial risk assessment

    Introducing confidence, adaptability and clarity into nanomaterial risk assessment

  • Facilitating decision-making in choice of techniques and SOPs

    Facilitating decision-making in choice of techniques and SOPs

How to overcome the data gaps in nanomaterial risk assessment

Between 500 and 2,000 nanomaterials (NMs) are expected to be placed on the EU market at volumes of at least 1 ton/year and are consequently affected by registration obligations under REACH and other legislations (e.g., for cosmetics). Testing of these NMs and updating the registration dossiers would entail costs of between €50 million and €315 million based on the proposed amendments to REACH guidelines for nanoforms. In silico approaches like QSAR, grouping or read-across, which are currently absent for NMs in large part as a result of data fragmentation and inaccessibility, would reduce this cost dramatically by removing the need for extensive laboratory and animal testing and would additionally improve our understanding of the biological and molecular mechanisms of toxicity of NMs. Douglas Connect will present at Nano Korea 2018 efforts for building a pan-European nanosafety knowledge infrastructure for organizing data, making it publicly accessible as well as integrating computational tools for risk assessment and decision support. Special focus will be on collection and management of data and experimental procedures annotated with rich metadata towards a complete characterization of the tested NM with respect to its physicochemical properties as well as human and environmental adversity.

This work was started in the eNanoMapper project delivering a nanomaterial ontology and a database concept and will be now continued in the NanoCommons and OpenRiskNet projects. Besides the successes in harmonization of data formats for standard methods, the ACEnano data warehouse concept will be presented as a specific example imposing high demands on the protocol and data management since early stages of method development and optimization without clear standard procedures have to be covered.

Royal Society of Chemistry – NPL Symposium, save the date!

Nanoparticle concentration – critical needs and state-of-the-art measurement symposium will be held on 24 April 2018 at Burlington House, London, organised by the Analytical Division East Anglia Region of the Royal Society of Chemistry (RSC) and the National Physical Laboratory (NPL).

It will bring together academics, measurement experts, instrument manufacturers, nanomaterials producers and industries interested in their use and applications to:

  • Discuss the state-of-the-art of nanoparticle analysis with focus on nanoparticle number concentration.
  • Present new methods to measure absolute nanoparticle concentration with low uncertainty, alongside the capabilities of a range of commercially available instrumentation.
  • Identify needs and potential pathways to address current limitations in methods, reference materials and protocols.
  • Discuss industrial requirements in the framework of product development, regulatory requirements and the development of standards.

Information of ACEnano will be displayed at the booth of one of its partners, PostNova Analytics. Feel free to ask them about our project!

More information here.

Stakeholder consultation on needs for nanomaterial physicochemical characterisation

ACEnano is running an online consultation for stakeholders with analytical characterisation needs in nanotechnology. The consultation is seeking to identify stakeholders who are interested in working with ACEnano to improve the project’s delivery of relevant and useful methodologies, tools and training materials for nanomaterial characterisation. The consultation can be found here and runs until 15th December 2017. 

Please take part on this consultation! The questionnaire should take no more than 5 minutes to complete and your responses will help to steer the project strategy towards your nanomaterial analysis needs.

Relevant papers published by Hanyang University

Hanyang University, member of ACEnano consortium, have recently published two relevant papers in which ACEnano project is acknowledged:

  • Enhancement of Catalytic Activity of Reduced Graphene Oxide Via Transition Metal Doping Strategy: HGLee_RGO_NanoResLett2017.pdf
  • Structural colour of unary and binary colloidal crystals probed by scanning transmission X-ray microscopy and optical microscopy Nho_STXM_PC_SciRep2017.pdf

Hope you find them interesting!

Save the dates for OpenTox Euro 2017 Meeting

We are happy to invite you to the OpenTox Euro 2017 Meeting to be held 21-23 November in Basel (Switzerland) at the Stücki meeting center.

This year’s program explores the major issues facing the European toxicology community, including Integration/interoperability, regulatory acceptance and the 3Rs (Replacement, Reduction and Refinement of Animal Testing).

Everyone concerned with designing a safer world is welcome at OpenTox Euro: researchers from academia and industry working in vivo, in vitro and in silico, risk assessors and regulators.

Our mission: Promote OpenTox as the place where the toxicology community talks across geographical, political, funding and field-of-expertise borders.

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